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Systems biology has long been interested in models capturing both metabolism and expression in a cell It is also the first to do so using common. A formulation for flux balance models accounting for expression, thermodynamics, and resource allocation constraints

To further increase its predictive power, the etfl model was designed to take into account a wide variety of measurements made through the massive field of omics, which measures. Scientists at epfl have developed an algorithm that can model biochemical reactions from metabolism down to rna synthesis with unprecedented accuracy.

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